Vaccine, mumps: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Parenteral
Active immunisation against mumps

Adult: 0.5 mL as a single dose via SC admin, preferably into the outer aspect of the upper arm.
Child: Given as a combination with measles and rubella vaccines: ≥12 mth: 2 doses of 0.5 ml via IM admin (SC admin if there is bleeding disorder). 1st dose is usually given after 1st birthday (recommended age: 12-15 mth) and 2nd dose at 3-5 yr or prior to school entry. Doses should be separated by at least 4 wk. May be given at any age if routine admin has been omitted. Immunisation dose given before 12 mth of age may not be effective long term and patients should be revaccinated with the 2 dose schedule.

Contraindications

Pregnancy. Hypersensitivity. Severe primary immunodeficiency; current treatment with chemotherapy or radiotherapy and within 6 mth of stopping such therapy; solid organ transplant patients receiving immunosuppressants, bone marrow transplant and for at least 12 mth after stopping immunosuppressive therapy, patients on high-dose systemic corticosteroids, HIV patients with immunosuppression.

Special Precautions

Women of child-bearing age should be vaccinated if they are seronegative; those who are found to be seronegative during pregnancy should be vaccinated in the early postpartum period. Not advisable to become pregnant within 1 mth of vaccination. Not recommended for children <1 yr. Allow alcohol or disinfectant that is used for skin cleansing to evaporate before vaccination to prevent inactivation of live vaccines. Bleeding disorders (use SC route).

Adverse Reactions

Skin rashes, pharyngitis, fever, and lymphadenopathy; arthralgia and arthritis may occur.

Pregnancy Category (US FDA)

Parenteral/SC: C (FDA Pregnancy Category C applies in combination w/ measles & rubella vaccines.)

Drug Interactions

Not to be given within 1 mth of admin of other live vaccines. Live vaccines should only be given at least 3 wk before or 3 mth after the use of immunoglobulin. Avoid admin during immunosuppressant or high dose systemic corticosteroid therapy.

Action

Description:
Mechanism of Action: The mumps vaccine is a preparation of live, attenuated organisms of the Jeryl Lynn (B level) strain of the virus.

Storage

Store at 2-8°C. After reconstitution, discard if not used within 8 hr.

MIMS Class

Vaccines, Antisera & Immunologicals

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